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Samman et al. Journal of Nutrition 2003

University of Sydney

Study summary and findings:

When compared to placebo, Juice Plus+ increased plasma levels of important antioxidant nutrients, folate, and a functional measure of plasma antioxidant capacity, while effectively decreasing homocysteine, an established risk factor for CHD.

This study measured the effect Juice Plus+ on plasma levels of selected vitamins, recognized coronary heart disease (CHD) risk factors, and general antioxidant status. Thirty- two healthy Australian men participated in this double-blind, placebo-controlled randomized crossover trial, consisting of two intervention periods of six weeks each, separated by a three week wash-out phase. During the intervention periods, subjects took either Juice Plus+ or placebo. Blood samples for nutrient analysis of and plasma antioxidant capacity were obtained at baseline, and again at the end of the third and sixth week for each intervention period. Plasma folate, vitamin C, alpha-tocopherol (vitamin E), retinol, and beta-carotene all increased significantly during the Juice Plus+ intervention period compared to placebo period. There was a trend (p = 0.065) for increased plasma antioxidant capacity, and a significant reduction in homocysteine during the Juice Plus+ intervention period.

Article Abstract: Journal of Nutrition 2003; 133 (7): 2188-2193

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